Senior Scientist, Antibody Engineering
IDPA78-2756175
Job TypeDirect Hire
Remote TypeOn-Site
Our client seeks a strategic Senior Scientist to join their Antibody Engineering team.
This individual will drive innovation in antibody discovery and engineering, integrating cutting-edge computational and experimental approaches to advance a pipeline of novel therapeutics.
The ideal candidate will take on the following responsibilities:
- Develop and advance next-generation antibody engineering methodologies, including structure-informed design, epitope-directed approaches, and affinity/specificity optimization, to expand platform capabilities across discovery and engineering campaigns.
- Design and execute antibody engineering strategies for challenging target classes, including membrane proteins and conformational epitopes.
- Integrate AI/ML and computational tools into antibody engineering workflows — leveraging generative protein design, protein language models, and in silico affinity prediction — to accelerate lead identification and optimization.
- Collaborate cross-functionally with structural biology, protein science, and computational teams to support end-to-end antibody development.
- Contribute to intellectual property strategy and advance scientific standing through inventorship and publications in high-impact venues.
- Present findings and progress to internal stakeholders and contribute to overall program strategy.
The ideal candidate will possess the following qualities:
- PhD in Immunology, Protein Engineering, Biochemistry, Molecular Biology, or a related field (or MS with significant relevant industry experience).
- Demonstrated experience in antibody engineering, discovery, or optimization (phage display experience welcomed but not required).
- Familiarity with structure-based design, computational tools, or AI/ML approaches to protein/antibody engineering is a strong plus.
- Track record of scientific contributions (patents, publications, or platform advancements).
- Strong collaborative and communication skills, with the ability to work cross-functionally.
My client offers the following:
- Competitive base salary ($120K–$140K) plus performance bonus.
- Relocation assistance.
- Opportunity to shape a growing antibody engineering platform at an expanding organization.