Molecular Laboratory Supervisor

Aurora, Colorado
Job TypeDirect Hire

Molecular Laboratory Supervisor

Overview

A growing, high-complexity clinical laboratory is seeking a Molecular Laboratory Supervisor to lead daily lab operations and support advanced molecular testing. This role blends hands-on technical expertise with team leadership, supporting cutting-edge diagnostics in genomics and molecular pathology.


Key Responsibilities

Technical Leadership

  • Perform and oversee molecular testing including DNA/RNA extraction, PCR, and Next-Generation Sequencing (NGS)
  • Lead assay development, validation, and optimization for somatic and germline testing
  • Analyze and interpret complex genomic data (ACMG/AMP guidelines)
  • Support testing across single-gene, panel, and whole genome platforms
  • Generate and review clinical reports

Laboratory Operations

  • Supervise high-complexity workflows and daily lab operations
  • Ensure compliance with CLIA, CAP, and HIPAA standards
  • Oversee QA/QC programs, SOPs, and validation processes
  • Troubleshoot instrumentation and workflows
  • Maintain inspection-ready lab environment

Leadership & Team Development

  • Supervise, mentor, and train laboratory staff
  • Assist in hiring and onboarding new team members
  • Maintain competency and training documentation
  • Lead team meetings and drive performance

Collaboration

  • Partner with lab leadership and cross-functional teams
  • Support process improvements and operational efficiency
  • Communicate findings through presentations and reporting

Qualifications

Education

  • Bachelor’s degree in a scientific discipline required
  • Master’s or PhD preferred (or equivalent experience)

Experience

  • Experience in a high-complexity molecular laboratory
  • Strong hands-on experience with NGS, PCR, and genomic analysis
  • Assay development/validation experience preferred
  • Prior leadership or supervisory experience is a plus

Certifications (Preferred)

  • ASCP, AMT, AAB, or equivalent certification

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