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The Pharmacometrics Group applies a range of model informed drug development (MIDD) approaches to support early and late-stage development of small and large molecules. We are seeking a skilled and qualified industrial scientist who has experience in planning and executing MIDD approaches to join us as a Principal Scientist. In this role, you will be responsible for the recommendation and implementation of pharmacometrics methodologies, contributes to internal and external clinical pharmacokinetic (PK) and pharmacodynamics (PD) modeling and simulation activities. Conducts PK/PD modelling and simulation in support of early stage programs or internal decision-making of late-stage programs. Will present modelling and simulation analyses to internal project teams and may present to external colleagues or regulatory agencies. You will work with experienced pharmacometricians, Preclinical Pharmacokinetics, Drug Metabolism, Toxicology, and Clinical Pharmacology colleagues to provide inputs to overall product development plans and to address research and development objectives and issues
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